Estrogen potentiation of the effect of thyrotrophin on thyroid 131I uptake in hypophysectomized female rats.
نویسندگان
چکیده
The daily administration of ƒÀ-estradiol benzoate (50ƒÊg or I mg) to hypophysectomized female rats for five consecutive days did not markedly alter 131I uptake by the thyroid gland. Estrogen or PMS increased thyroid uptake of 131I in TSH treated hypophysectomized rats. Similar results were obtained with estrogen but not PMS in hypophysectomized and oophorectomized animals. These observations show that estrogen can potentiate the TSH induced uptake of 131I by an extrapituitary mechanism.
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ورودعنوان ژورنال:
- Endocrinologia japonica
دوره 13 3 شماره
صفحات -
تاریخ انتشار 1966