Estrogen potentiation of the effect of thyrotrophin on thyroid 131I uptake in hypophysectomized female rats.

نویسندگان

  • T Sato
  • S Matsumoto
چکیده

The daily administration of ƒÀ-estradiol benzoate (50ƒÊg or I mg) to hypophysectomized female rats for five consecutive days did not markedly alter 131I uptake by the thyroid gland. Estrogen or PMS increased thyroid uptake of 131I in TSH treated hypophysectomized rats. Similar results were obtained with estrogen but not PMS in hypophysectomized and oophorectomized animals. These observations show that estrogen can potentiate the TSH induced uptake of 131I by an extrapituitary mechanism.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Multiple non-malignant iodine uptake in a 131I whole body scan of a patient with papillary thyroid carcinoma: Importance of SPECT/CT

After thyroidectomy in papillary thyroid carcinoma (PTC) patients, whole body radioiodine scan (WBIS) is necessary for localization of any abnormal radioiodine avid lesions. However false-positive radioiodine uptake in WBIS can be problematic. We report a 32 years old female patient with PTC. After thyroidectomy and radioiodine therapy WBIS was performed. In her post therapy WBIS, there were zo...

متن کامل

The effects of high calcium intake on the activity of thyroid gland in rats

The effects of goitrogens on the thyroid gland have been much studied and calcium is considered as a goitrogen in some cases. Since the level of calcium is high in drinking water of some cities of Khozestan province, the effects of high calcium intake on the function of thyroid gland is investigated in this study. For this purpose the concentration of thyroid hormones is measured in rats. The s...

متن کامل

The effect of intrastriatal injection of estrogen on pallidal field potential and rigidity in Parkinsonian -ovariectomized rats

The major pathological feature of Parkinson’s disease (PD) is a progressive loss of dopamine-producing neurons of the substantia nigra pars compacta (SNc), resulting in a reduction of dopamine (DA) content in the target field of these neurons, the striatum (STR). The present evidences suggest that female sex hormones may influence the onset and severity of PD symptoms. PD is more prevalent in m...

متن کامل

Extremity Radioactive Iodine Uptake on Post-therapeutic Whole Body Scan in Patients with Differentiated Thyroid Cancer

Objective(s): We investigated a frequency of lower extremity uptake on the radioactive iodine (RAI) whole body scan (WBS) after RAI treatment in patients with differentiated thyroid cancer, in order to retrospectively examine whether or not the frequency was pathological. Methods: This retrospective study included 170 patients with thyroid cancer, undergoing RAI treatment. Overall, 99r (58%) an...

متن کامل

Multihormonal regulation of hepatic sinusoidal Ntcp gene expression.

Bile acids are efficiently removed from sinusoidal blood by a number of transporters including the Na+-taurocholate-cotransporting polypeptide (Ntcp). Na+-dependent bile salt uptake, as well as Ntcp, are expressed twofold higher in male compared with female rat livers. Also, estrogen administration to male rats decreases Ntcp expression. The aims of this study were to determine the hormonal mec...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Endocrinologia japonica

دوره 13 3  شماره 

صفحات  -

تاریخ انتشار 1966